Bladder Cancer & Treatment Options

At Pioneer Valley Urology, we are dedicated to providing comprehensive, state-of-the-art care for patients facing bladder cancer serving the Greater Springfield area and Northern Connecticut. With a commitment to early detection and advanced treatment options, our team ensures that every patient receives personalized, compassionate care tailored to their needs. Bladder cancer is a serious but treatable condition, and our goal is to guide patients through every step of their journey toward recovery.

Understanding Bladder Cancer

Bladder cancer develops in the cells of the bladder, the organ responsible for storing urine. The most common type is urothelial carcinoma, which begins in the inner lining of the bladder. If left untreated, it can become invasive, spreading through the bladder wall and potentially affecting nearby tissues and organs. Early detection plays a critical role in effective treatment.

Types of Bladder Cancer

Bladder cancer is categorized based on the type of cells where it originates:

  • Urothelial Carcinoma: The most common type, developing in the urothelial cells lining the bladder.

  • Squamous Cell Carcinoma: A rare form arising from squamous cells, often linked to chronic irritation or infection.

  • Adenocarcinoma: The rarest form, originating in mucus-producing glandular cells within the bladder.

Risk Factors for Bladder Cancer

While the exact cause is unknown, several factors increase the likelihood of developing bladder cancer:

  • Smoking (the leading preventable cause)

  • Advancing age

  • Male gender

  • Caucasian ethnicity

  • Family history of bladder or other cancers

  • Chronic exposure to carcinogens (e.g., industrial chemicals)

  • Prior cancer treatments, such as pelvic radiation or chemotherapy with cyclophosphamide

Symptoms of Bladder Cancer

Common symptoms include:

  • Blood in the urine (hematuria), often painless

  • Frequent or painful urination

  • Pelvic or lower back pain

These symptoms overlap with other urological conditions, so accurate diagnosis is essential.

Diagnosis of Bladder Cancer

At Pioneer Valley Urology, we utilize state-of-the-art diagnostic tools, including:

  • Urine Cytology and FISH Testing: Advanced tests to detect cancerous cells in urine.

  • Cystoscopy: A procedure using a thin, lighted scope to examine the bladder.

  • Biopsy: Removing tissue samples for analysis.

  • Imaging Tests: Such as CT scans, MRIs, or PET scans to evaluate the extent of the disease.

Stages of Bladder Cancer

Bladder cancer stages range from:

  • Stage I: Limited to the bladder’s inner lining

  • Stage II: Invading the bladder muscle

  • Stage III: Extending beyond the bladder wall to nearby tissues

  • Stage IV: Spreading to lymph nodes or other organs

Cutting-Edge Treatment Options

Our team offers comprehensive and modern treatments tailored to each patient’s unique needs. These include:

Bladder-Sparing Therapies

  • BCG Therapy: Bacillus Calmette-Guerin (BCG) immunotherapy stimulates the immune system to attack cancer cells. This is the gold standard for high-grade, non-muscle-invasive bladder cancer.

  • Intravesical Chemotherapy: Anti-cancer drugs like mitomycin or gemcitabine are delivered directly into the bladder to target cancer cells while sparing healthy tissue.

  • Adstiladrin Therapy: A groundbreaking gene therapy for non-muscle-invasive bladder cancer, Adstiladrin uses an adenoviral vector to deliver gene-based treatment, providing an innovative, bladder-sparing option.

Surgical Options

  • TURBT (Transurethral Resection of Bladder Tumor): A minimally invasive procedure to remove tumors from the bladder lining.

  • Cystectomy: Partial or complete bladder removal for advanced cases, often combined with reconstructive options like neobladder creation or ileal conduit.

Systemic Therapies

  • Chemotherapy: Used for advanced or metastatic bladder cancer, systemic chemotherapy destroys cancer cells throughout the body.

  • Immunotherapy: Treatments like checkpoint inhibitors (e.g., pembrolizumab) harness the body’s immune system to fight cancer.

Radiation Therapy

High-energy radiation targets and kills cancer cells, often used in combination with other treatments.

Why Choose Us?

Pioneer Valley Urology stands at the forefront of bladder cancer care in Greater Springfield and Enfield, CT. Our expert team is dedicated to utilizing the latest advancements in diagnosis and treatment, ensuring personalized, compassionate care for every patient. We pride ourselves on being leaders in bladder-sparing therapies, including Adstiladrin and intravesical treatments.

Prevention and Support

While bladder cancer cannot always be prevented, risk can be reduced by:

  • Quitting smoking

  • Limiting exposure to harmful chemicals

  • Staying well-hydrated

  • Maintaining a healthy diet

We also provide ongoing support and education to empower our patients and their families throughout the treatment journey.

Contact Us

If you or a loved one has concerns about bladder cancer, contact Pioneer Valley Urology today. We proudly serve the Greater Springfield and Enfield, CT communities with expert, compassionate care. Schedule an appointment at www.pvurology.org or call us to learn more about our advanced bladder cancer treatments.

Additional Resources

Our Urologists

Kevin Asher, MD

Kevin Asher, M.D. graduated from Towson University and Columbia University Medical School. He completed his residency in Urology at Boston University and has completed a fellowship in Urologic Oncology at the N

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Aaron Berkenwald, M.D.

Dr. Berkenwald received his medical degree from the University of Massachusetts Medical School, and he completed his surgical and urological residency at Lahey Medical Center. He graduated summa cum laude from Nor

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Stephen Gallo, MD

Dr. Gallo received his BA Degree from Johns Hopkins University and his medical degree from New York Medical College. He completed his training in urology at New York Medical College. Dr. Gallo is the Chief of Urol

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Andrew Kim, MD

Dr. Kim received his medical degree from University of Maryland School of Medicine, and he completed his surgical and urological residency at University of Maryland Medical Center. He earned his BS degree in Mecha

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Joshua Pagar, MD

Dr. Pagar received his medical degree from St. Louis University School of Medicine, and completed his surgical and urological residency at University of Missouri Hospital and Clinics, Columbia, MO. He earned his M

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Joseph Sarcona, MD

Dr. Sarcona received his medical degree from New York Medical College, Valhalla, NY, and he completed his surgical and urological residency at Lenox Hill Hospital, New York, NY. He earned his BS degree in Neurosci

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Jonathan Starkman, MD

Dr. Starkman received his bachelor of science degree in molecular biology, from the University of Michigan and his medical degree from Wayne State University School of Medicine, Detroit, MI. He completed his train

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William Swanson, MD, MBA

Dr. Swanson received his bachelor of arts degree, with honors and in biology, from the University of Massachusetts, Boston, Massachusetts. He received his medical degree from Albany Medical College in 1995, where

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Michael Zavaski, MD

Dr. Zavaski received his medical degree from University of Connecticut School of Medicine, and he completed his surgical and urological residency at Harvard Program in Urology- Brigham and Women's Hospital in Bost

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